Dangerous Drug Combinations: What Every Doctor Should Know

Here are some contradicted combinations of drugs in modern medicine that every doctor should know and avoid giving to patients.
Contraindication of Drugs - Medical Knowledge for Doctors
Greetings Doctors, I am Dr.Himanshu Jha. In this article, we will explore some of the contraindicated combinations of drugs in modern medicine that every doctor should know and avoid prescribing to patients.
As you may recall, in our previous article, we discussed the topic “BAMS Duty Doctor Job Interview: What Salary to Expect and How to Prepare?” If you have not read that article yet, you can find it on Ayurveda Siddhi.
Today’s topic is “Contraindications of Drugs”. In Ayurveda, we have the concept of Virudh Aahara (Incompatible food) that can cause adverse effects on the body. Similarly, in allopathy, we have the concept of Virudh Ausadh (Incompatible drugs) that can cause harmful interactions when taken together. These drug combinations should be avoided by doctors. In this article, I will explain why these combinations are dangerous and what symptoms they can cause.
Don’t give with Because (Reason)
Tetracyclines Penicillins tetracyclines are bacteriostatic and inhibit the growth of bacteria and penicillins work only on actively dividing organisms.
Azithromycin Antihistamines severe chest pain and prolong QT interval
Anti-acid or anti-ulcer medication Iron in pt. with IDA iron needs acidic media to be absorbed.
Metronidazole Warfarin Metronidazole inhibits the metabolism of warfarin by blocking (CYP-2C9) which may lead to fatal bleeding
furosemide (lasix) Gentamycin maybe lead to hearing loss
Non-dihydropyridine (Verapamil & diltiazem) Beta-blocker both of them cause Severe bradycardia & heart block
Nifedipine or any drug ending with “dipine” Nitrate both of them cause vasodilation & Severe hypotension
Sildenafil (Viagra) Sublingual nitroglycerin both of them cause vasodilation –> Severe hypotension & may be death
Omega 3 Antiplatelet or Anticoagulant Because it causes bleeding
Statin Gemfibrozil increase the risk of the myopathy
Ciprofloxacin, Clarithromycin, Cimitidine, Fluvoxamine & erythromycin theophylline these drugs are Cyp450 inhibitors that lead to inc. in the theophylline level in the blood leading to death
Warfarin NSAIDS increase the risk of the GIT bleeding
Omperaszole Clopidogrel (Antiplatelet) Omeprazole decreases the effect of the clopidogrel by affecting the hepatic enzyme CYP2C19 metabolism
K_ sparing diuretics ( amiloride & Spironolactone ) ACEI ( captopril ) lead to hyperkalemia
Also Read this  Effect of Agnikarma on Body | How AgniKarma works? by Ayurveda Sidhi

We are delighted that you found this web page and we hope you will share it with other Doctors who might benefit from it. This blog is a valuable resource for medical students and Doctors who want to learn more about various topics in medicine.

Disclaimer: The content of this blog is for educational purposes only and does not constitute medical advice. We do not claim to be experts or authorities on any subject matter. We do not endorse any products or services mentioned on this blog. You should always consult with a qualified healthcare professional before making any decisions based on the information on this blog. We are not liable for any harm or injury that may result from the use or misuse of the information on this blog.

Message from Vd.Himanshu Jha (Admin):- 

Hello everyone,

Our aim is to help each other by providing study resources for bams students. We believe that sharing knowledge and learning together can improve our clinical knowledge and confidence. Therefore, we request everyone to participate actively and contribute to the group. So please, don’t be shy and contribute whatever you can, and feel free to post your questions, doubts, tips, notes, or any other useful material that you think can benefit others. Thank you for joining us and let’s make this a productive and enjoyable experience. If you have not joined us yet then links are given below. Do support us on social media.

Join Whatsapp Group Click Here
Join Telegram Channel Click Here
Subscribe Youtube Channel Click Here
Follow on Instagram Click Here

Leave a Reply

Your email address will not be published. Required fields are marked *